BONE MARROW STEM CELLS

Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. The postnatal bone marrow has traditionally been seen as an organ composed of two main systems rooted in distinct lineages—the hematopoietic tissue and the associated supporting stroma. The evidence pointing to a putative stem cell upstream of the diverse lineages and cell phenotypes comprising the bone marrow stromal system has made marrow the only known organ in which two (or more) separate and distinct stem cells and dependent tissue systems not only coexist but functionally cooperate, defining hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs).